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Traditional 2-D cell cultures are longstanding and effective models used in basic cancer research. If this in vivo- GEP-normalization would materialize, screening data generated in the cell line in vitro could point to which PDX model to use for accurate in vivo validation. Annals of surgery, Journal article Journal article. Staging and therapy for patients with hepatocellular cancer in a defined population from to - active palliative treatment improved overall survival. One of many possible explanations for reduced total RB could be reduced cap-dependent translation in response to hypoxia [ 26 ]. Infectious diseases London, EnglandMagazine article Magazine article Read the full text on a web page.

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Oncological outcome and aspects of self-assessed quality of life Mattias Prytz Doctoral thesis Doctoral thesis Read the full text on a web page.

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Department of Surgery

Latest publications miRNA profiling of small intestinal neuroendocrine tumors defines novel molecular subtypes and identifies miR as a biomarker of patient survival Yvonne ArvidssonAnna RehammarAnders BergströmEllinor AnderssonGülay Altiparmak et al. In light of our results and the known culture adaptions of cell lines it is tempting to speculate that cell lines transplanted into mice may experience stress due to the physiological growth factor availabilities, oxygen tension and glucose levels, which are all lower than in cell culture. This makes biomarker discovery possible prior or parallel to clinical trials [ 1617 ]. Geminin, an inhibitor of DNA replication, is degraded during mitosis. An obvious difference could be that in our system, we blocked hsa-miR function in the tumor cells only and the cells were grown in an immune compromised host. You may now see our list and photos of women who are in your area. Indeed, 3D cell cultures are viewed as better predictors of therapy responses in vivo than 2D cultures [ 35 ].

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  • Zachariah 11 days ago

    This bitch is all thighs and ass

  • Deandre 18 days ago

    This gal is hot!

  • Brian 24 days ago

    She's pregnant again. Looks like she's got a baby bump in this scene.